Showing posts with label aids vaccine. Show all posts
Showing posts with label aids vaccine. Show all posts

Friday, February 15, 2008

Interesting developments on the AIDS frontiers

I suspect you might have missed one or another of the big-news events on the AIDS fronts. Nobel laureate and current president of the AAAS David Baltimore used his keynote address to the AAAS meeting this year to suggest that there's a distinct possibility (not to say high likelihood) that we won't be getting a successful preventive HIV vaccine ever.

The excitement over findings that male circumcision might drastically reduce HIV risk should be somewhat cooled down, because another study since discovered in the USA that that actually wasn't the case for circumcised black and latino men who have sex with other men.

Another piece in the puzzle is a consensus statement from HIV/AIDS specialists in Switzerland who declared that it is impossible for an HIV infected person to pass the infection on to his or her sex partners if she's on HAART and has a viral load of less than 40 copies/ml. In other words, successful medical control of the infection renders infected people non-infectious for all intent and purposes.

Indeed, it has even been suggested by some scientists that pre-exposure prophylaxis might work (ie people who are at high risk of getting infected should take AIDS drugs as a preventative means). Of course, today's AIDS drugs are essentially chemotherapeutics, so to suggest that healthy people at risk of HIV infection take them permanently (or at least while they engage in high-risk activities) seems a difficult to accept proposition, yet it might well work (just as post-exposure prophylaxis works) while there's no vaccine.

However, all of these discussions seem to be indicative of an ever-growing desperation among HIV specialists resulting from the absence of a working vaccine. The ongoing AIDS epidemics among the peoples of Southern Africa and the Caribbean suggest strongly that only so much can be achieved by throwing condoms at people... and so much, quite possibly, just isn't good enough. This is not the type of politically correct message the safe sex industry likes to hear, but surely the pandemic would not continue to run at such high speed if the safe sex campaigners had made significant inroads during the last few decades. To be fair, it might be that safe sex is currently more or less all there is, but it would be wrong to pretend that it is 'working' as they say.

Of course, living in North America these days, I do have access to truly bizarre religious cable channels. This crowd is actually trying to persuade Africans not to use condoms and instead be abstinent. I watched a fundraising programs from them the other day, in which these folks deliberately spread falsehoods such that condoms have little holes in them thru which HIV can spread anyway, and other such nonsense. It boggles the mind. The biggest lies were peddled by a guy in a black (long) skirt with a white collar - he claims, of course, to never have had sex in his whole life. These are the types of characters that, in yet another wave of Western colonialism, travel to Africa and try to persuade rural Africans to forgo the use of condoms when they've sexual intercourse.

Scary stuff. Well, it seems there's always someone out there to make matters worse, and the religious squad is never far from where that happens. As ever, due to some waffle about religious freedom, they cannot even be held accountable in a court of law for spreading lies.

Thursday, November 29, 2007

Robbing Peter to pay Bill: Mr Harper does AIDS

One must congratulate the Federal government of Canada on a pretty brilliant political move in terms of how it allocates its AIDS related resources. Mr Harper's government has decided to reallocate about 26 mio C$ within its AIDS budget. This amount is re-routed away from programs the government does not fancy much, politically. Funding for Ontario's community programs reportedly will be slashed by up to 30%. As one would expect, there has been quite a bit of an uproar in the community, ranging from gay men's AIDS groups to NGOs offering needle exchange programs to injecting drug users. So, all this looks much like a conservative government in conservative policy making action. On the face of it one should go about waving hands and writing bitter letters to newspaper editors - of which, no doubt, there will be many. After all, harm minimization programs for IV drug users work to some extent, and in light of rising numbers of HIV infections among gay men, any half-educated public health practitioner would have reason to be up in arms against Mr Harper's policies. Predictably, unless the provincial government steps in or other sources of funding for such community groups can be found, HIV infections will increase in Canada as a result of the cuts.
Here then is the brilliant bit of the government move. It re-routed the funding not to some conservative pet project or other, but to the Gates' Foundation's Vaccine Initiative. Gates offers to match every dollar provided with the foundation's own funds (well, really the taxes we pay to Microsoft for using its ubiquitous software). So, money is ultimately removed from the immediate fight against AIDS in Canada to the fight against AIDS in the world, particularly so in the developing world. After all, the ultimate solution to AIDS will not be found in prevention programs, it will be in a preventive vaccine - or it won't be a solution to begin with. It is that simple. While it is a bit surprising for a conservative government - actually, for any government - to prioritize much larger needs elsewhere over needs at home, arguably that is what we ought to do. If ever there was a policy aiming at the greatest good for the greatest number, this would probably qualify. A very ethical choice indeed! Or so it seems.
At a first glance, community based AIDS organizations criticizing Harpers government seem selfish at best. But only at a first glance, because, truth be told, in the big swing of things in the federal budget, these few millions to community based AIDS organizations are really neither here nor there. It would have been more than easy for Mr Harper's government to find the money for the Canadian AIDS vaccine initiative elsewhere if it had put its mind to it. There can be little doubt, the 'robbing peter to pay bill' kind of decision making that we are witnessing here, is politically motivated and has nothing at all to do with international public health priorities. The government's grand gesture in response to Mr Gates' even grander gesture suggests that some kind of hard ethical decision had to be made, when really there was no need for this at all.
We should wave our hands and write bitter letters to newspaper editors after all... unfortunately.

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